Genomics on PYRAX
Genomic data is the most personal, immutable, and re-identifiable data a person owns — yet research demands it be pooled at scale. PYRAX resolves the tension with PYRAX Compute compute-to-data, so models train on private genomes in place, patients hold cryptographic consent over every use, and results are verifiable while raw sequence never leaves its custodian.
The market
Source: Grand View Research, 2024. Figures are indicative and provided for context.
What's broken today
How PYRAX transforms it
Concrete network elements mapped to this business.
PYRAX Compute compute-to-data
GWAS, polygenic-risk, and variant-effect models train and infer directly on private genomes at each biobank, returning verifiable results without the sequence ever moving.
Consent-gated data with revocation
Every model run requires the participant's on-chain consent for that specific purpose, and consent is revocable, giving true dynamic control.
Shielded-by-default genomic commitments
Genomes are held off-chain; only commitments and result proofs are on-chain, so there is no re-identifiable data on the ledger.
eth_getProof result provenance
Each analysis result carries a proof of which model, data, and consents produced it — an auditable lineage for IRBs and publications.
On-chain escrow for data value-return
When a participant's data contributes to a study, escrow can return value or fund a data trust, aligning incentives with the individuals who own the genome.
Buildathon: dApp ideas
Ship-ready concepts for genomics on PYRAX.
GenomeVault
01Custodian-held genome store exposing only commitments; all use flows through PYRAX Compute compute-to-data.
ConsentGene
02Dynamic genomic-consent wallet granting and revoking per-study, per-purpose access.
FederatedGWAS
03Cross-biobank association study running in place with verifiable pooled statistics and no raw-data exchange.
RiskScoreAI
04Polygenic-risk inference a patient runs on their own genome, receiving results without exposing SNPs.
LineageProof
05Result-provenance explorer showing exactly which data and consents produced each finding via eth_getProof.
DataDividend
06Escrow contract returning value to participants when their genomic data contributes to a funded study.
VariantRegistry
07Shielded pathogenic-variant registry letting labs share evidence commitments without exposing patients.
PharmacoGeneKey
08Consent-gated pharmacogenomic report a patient shares with a prescriber via scoped viewing key.