Genomics on PYRAX

Genomic data is the most personal, immutable, and re-identifiable data a person owns — yet research demands it be pooled at scale. PYRAX resolves the tension with PYRAX Compute compute-to-data, so models train on private genomes in place, patients hold cryptographic consent over every use, and results are verifiable while raw sequence never leaves its custodian.

Market size
$32.4B genomics market (2024)
Projection
$94.7B by 2030 · ~19.6% CAGR

The market

~19.6%
Genomics market CAGR to 2030
<$200
Cost to sequence a human genome
yes
Genome data re-identifiable from SNPs
vast majority
Participants wanting control over data use

Source: Grand View Research, 2024. Figures are indicative and provided for context.

What's broken today

Genomic data is permanently re-identifiable, so any breach is irreversible and lifelong.
Research requires large cohorts, but pooling raw genomes creates unacceptable privacy risk.
Patients rarely control or profit from downstream use of their own genetic data.
Provenance and consent for each genomic use are hard to prove to IRBs and regulators.

How PYRAX transforms it

Concrete network elements mapped to this business.

PYRAX Compute compute-to-data

GWAS, polygenic-risk, and variant-effect models train and infer directly on private genomes at each biobank, returning verifiable results without the sequence ever moving.

Consent-gated data with revocation

Every model run requires the participant's on-chain consent for that specific purpose, and consent is revocable, giving true dynamic control.

Shielded-by-default genomic commitments

Genomes are held off-chain; only commitments and result proofs are on-chain, so there is no re-identifiable data on the ledger.

eth_getProof result provenance

Each analysis result carries a proof of which model, data, and consents produced it — an auditable lineage for IRBs and publications.

On-chain escrow for data value-return

When a participant's data contributes to a study, escrow can return value or fund a data trust, aligning incentives with the individuals who own the genome.

Buildathon: dApp ideas

Ship-ready concepts for genomics on PYRAX.

GenomeVault

01

Custodian-held genome store exposing only commitments; all use flows through PYRAX Compute compute-to-data.

Computecompute-to-dataZK

ConsentGene

02

Dynamic genomic-consent wallet granting and revoking per-study, per-purpose access.

consentrevocablepatient

FederatedGWAS

03

Cross-biobank association study running in place with verifiable pooled statistics and no raw-data exchange.

ComputefederatedAI

RiskScoreAI

04

Polygenic-risk inference a patient runs on their own genome, receiving results without exposing SNPs.

Computeprivacyinference

LineageProof

05

Result-provenance explorer showing exactly which data and consents produced each finding via eth_getProof.

eth_getProofprovenanceaudit

DataDividend

06

Escrow contract returning value to participants when their genomic data contributes to a funded study.

escrowincentivesEVM

VariantRegistry

07

Shielded pathogenic-variant registry letting labs share evidence commitments without exposing patients.

ZKcommitmentresearch

PharmacoGeneKey

08

Consent-gated pharmacogenomic report a patient shares with a prescriber via scoped viewing key.

viewing-keysconsentclinical